News for 2009

Makers of generic Reglan liable for inadequate warning labels

judge gavelMakers of generic drugs who do not adequately label their products to warn consumers of possible risks are not exempt from liability, according to a ruling by the U.S. Court of Appeals for the Eighth Circuit. The court ruled on a product liability lawsuit brought by Gladys Mensing, who was prescribed metoclopramide to treat diabetic gastroparesis, a debilitating condition in which the stomach empties too slowly. Following use of the medication, Mensing developed a serious movement disorder known as Tardive Dyskinesia. Research has shown that the condition can be caused by long-term use of . Mensing sued several makers of generic , known by the brand name Reglan, for not adequately warning consumers of the risk of developing the movement disorder.

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Gastroparesis organization raises awareness through video

The Gastroparesis Awareness Campaign Organization has released a video to help raise awareness of the seriousness of the condition in which the stomach takes too long to digest food. The video, called The Faces of Gastroparesis 2009, can be seen on YouTube, and here:

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People of all ages, shapes and sizes suffer from gastroparesis. The National Institutes of Health estimates as many as 10 million people are living with gastroparesis. Because of the lack of medical education and improper diagnosis, many more may be suffering in silence. Symptoms include abdominal cramps, nausea and vomiting and can result in dehydration, electrolyte imbalances and malnutrition.

Treatments include medication, such as Reglan (metoclopramide), and surgery. Those with gastroparesis suffered yet another blow this year when the Food and Drug Administration (FDA) issued a on after numerous cases of a serious movement disorder known as Tardive Dyskinesia were reported in patients who took . Long-term users were as much as 20 percent at risk of developing the condition.

Because treatments offer only temporary benefits to patients, activists groups such as the Gastroparesis Awareness Campaign Organization are working to raise awareness in hopes of finding better, safer treatments and, eventually, a cure.

Long term use of heartburn drugs can be dangerous

heartburn 150x150 Long term use of heartburn drugs can be dangerousMillions of people turn to medication to treat the annoying and painful symptoms of heartburn. But doctors say that people who use medications to treat their symptoms should use them with caution and limit use if at all possible.

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Reglan may calm chronic sneezing fits, but long-term use risky

Sneezing 150x150 Reglan may calm chronic sneezing fits, but long term use riskyLast month, a 12-year-old girl’s mysterious sneezing illness promoted a flurry of attention after her story was told on MSNBC’s Today show. Lauren Johnson sneezes 10 times a minute – up to 12,000 of times a day – and doctors have no clue why. Weeks later she was diagnosed with Paediatric Autoimmune Neuropsychiatric Disorder Associated with Streptoccus, or PANDAS. Her parents say that antibiotics have improved her disorder, but that she is at risk of showing symptoms again in the future.

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New heartburn medication meets expectations in drug trial

Addex Logo V21 New heartburn medication meets expectations in drug trialSwiss biotech group Addex Pharmaceuticals announced that its lead drug candidate met expectations in a mid-stage clinical trial in heartburn, setting the company up for a lucrative partnership with a bigger drug maker that would provide much-needed funds for the startup company.

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FDA approves generic GERD treatment

nizatidine 150x150 FDA approves generic GERD treatmentThe Food and Drug Administration (FDA) has approved a generic version of a drug for treating gastroesophageal reflux disease, or GERD, in adolescents and adults. Amneal Pharmaceuticals’ nizatidine oral solution was approved in the 15-mg-per-15-ml strength, and is a generic version of Axid, made by Braintree Laboratories. The medication belongs to a class of drugs known as histamine H2 blockers.

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New study may lead to different treatments for GERD

gerd stomach 2Findings from a new study on the causes of gastroesophageal reflux disease (GERD) may lead to new way of treating the condition. According to a team of researchers from the University of Texas Southwestern Medical Center, GERD, which causes painful chest pain and heartburn, may be caused by immune system cells causing inflammation. The study showed that gastroesophageal reflux in rats causes tissue in the esophagus to release immune chemicals called cytokines. Those cytokines attract inflammatory cells that cause the uncomfortable symptoms associated with heartburn and GERD.

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Reglan may stop hiccups, but may cause more serious problems

hiccups 150x150 Reglan may stop hiccups, but may cause more serious problemsMost people who take the medication Reglan (metoclopramide) are prescribed the drug to treat heartburn, GERD, or gastroparesis, also known as slow emptying of the stomach. But may also halt persistent hiccups.

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Non-surgical procedure offers hope to patients with GERD

surgical specialistsPatients who suffer from gastroesophageal reflux disease (GERD) often have to give up their favorite foods because of bothersome symptoms, which can include chronic heartburn, acid reflux, difficulty swallowing and constant belching. Medications can help but they sometimes come with irritating side effects. But a new procedure is offering hope for patients who suffer from GERD.

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Pacemaker gives hope to sufferer of gastroparesis

gastric pacemakerThirty-two-year-old Shimmi Munshi would get sick up to 50 times a day over a four-year period, but doctors were at a loss as to why. She was put on feeding tubes and medication, but the treatments did little to help her. She became sicker and weaker. It wasn’t until the young woman scoured the Internet that she some answers. She immediately diagnosed herself with gastroparesis, or paralysis of the stomach. And found a treatment that would help her live a normal life. 

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