Women warn new mothers of Reglan’s depression risk
It might surprise some to learn that the prescription heartburn drug Reglan (metoclopramide) has an off-label use of helping new mothers increase their milk supply. An appropriate level of the hormone prolactin permits lactation to proceed normally, but when a mother has low prolactin levels, milk supply may suffer. Drugs used to stimulate lactation work by blocking dopamine, which results in increased prolactin levels and, in many cases, an increase in milk supply.

