Acid reflux drugs provide temporary relief but can cause adverse reaction
Severe acid reflux or heartburn can be painful and bothersome with symptoms that range from chest pain or a burning esophagus to hoarseness and sore throat. There are several methods to treat the condition such as manipulating the stomach acid secretion by neutralizing the acid, blocking the Histamine2 to stop acid production, or blocking the gastric proton pump. While the host of over-the-counter and prescription drugs to treat acid reflux can bring temporary relief, long-term use of acid reflux drugs can lead to some alarming adverse reactions.
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Swiss biotech group Addex Pharmaceuticals announced that its lead drug candidate met expectations in a mid-stage clinical trial in heartburn, setting the company up for a lucrative partnership with a bigger drug maker that would provide much-needed funds for the startup company.
Taking popular medications to treat symptoms of heartburn and gastroesophageal reflux disease (GERD) may actually make those symptoms worse, according to a recent study in Gastroenterology, the official journal of the American Gastroenterological Association Institute. Those medications – called proton pump inhibitors (PPI) and known by the brand names Prilosec, Nexium, Prevacid, and Aciphex – have even been linked to other serious complications such as dizziness, osteoporosis, pneumonia and heart attacks, according to